应该没有画错,这是原文中的描述
[For better convergence of the free energy profile, the ‘tagged’ particle needs to sample a significant fraction of the individual local minima and the saddle points connecting them. For instance, in Fig. 5, the free energy barrier measures 0.24 eV after 10 ns, while from 20 ns onward, the barrier starts converging, and settles to the value of 0.34 eV over the period of 100 ns]
还有个图也是类似的趋势,我倾向于他没有画错,因为在我的MTD FES里也遇到了类似的问题 作者Author: fhh2626 时间: 2022-1-6 10:49
当然是可能的,自由能面是相对高度,其他地方高了就相当于最高点下降了作者Author: 函数与激情 时间: 2022-1-6 12:07