Funded PhD Project in De Montfort University (Students Worldwide) - 计算化学公社

About the Project
We lack a fundamentalunderstanding of how molecular structure relates to the properties offluorescent molecules, including how fluorescence varies with pH. This makes ithard to design fluorescent probes for use in environments, like the lysosomallumen, where pH is not constant. This project will prepare a matrix offluorophores from a number of different families and investigate how theirfluorescence varies with parameters such as solvent, pH, temperature andviscosity. This systematic study will help progress our understanding offluorophore chemistry from the current trial-and-error to molecularengineering. The discoveries will be applied to the development of fluorescentprobes for lysosomal K+ and Ca2+ - these ion populations have been implicatedin various disease states including neurodegeneration.
Enquiries
Potential applicants cancontact Dr Simon Wheeler, for any questions about the project or for informalenquiries (simon.wheeler@dmu.ac.uk).
Applicants must:
Possess a UK Honoursdegree with at least an upper second class, or overseas equivalent degree, or arelevant Masters qualification.
Demonstrate competencein the use of the English language. Please see section 5b here for furtherdetails on meeting our English language entry criteria.
The deadline to apply isMonday 15th July 2024.
Information on how toapply for this scholarship please visithttps://www.dmu.ac.uk/doctoral-college/study/scholarships.aspx )
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Funding Notes
The full studentship(tuition fees and salary stipend) is eligible to home and internationalstudents, commencing on 1st October 2024.