alphafold2

tanyingjia 发表于 2021-11-10 12:39
Okay, I probably understand what you mean, I'll try it。Thanks！

how to try ,can you explain in detail ？

Okay, I probably understand what you mean, I'll try it。Thanks！

you can get it by homology modeling, you can get the same structure you get from the modeling as template and get a new structure, using modeller or swiss-model to model that parts and bind together

嗯嗯，因为我确实需要末端770多-800号残基，对接小分子

开始和结束的部分不一定能构成有意义的二级结构，你看看PDB给的蛋白质结构，要是缺失的部分不影响整体结构就当没看见得了。