CADD Scientist→Director
Direction：Small molecule
Base：Shanghai、Beijing
Responsibilities:
1. Support/drive early discovery projects from target identification/evaluation to hit identification, to lead optimization, and all the way to PCC and IND-enabling studies
2. Contribute to the hit/lead optimization campaigns through mitigating any detected liabilities in terms of potency, selectivity, and ADME/PK profiles
3. Contribute to the global AI platform in optimizing current tools or establishing novel AI/machine learning models in cheminformatics and/or molecular modeling areas, which are applicable to discovery projects
4. Proactively integrate experimental data and apply computational approaches to generate knowledge and insights
Requirements:
1. PhD in computational chemistry/ biology, CADD, or any relevant areas that also bring the following set of skills and expertise
2. Proficient in structure-/ligand-based drug design, including molecular docking, virtual screening, QSAR, homology modeling, molecular dynamics, and quantum mechanics, etc., and master the relevant tools, including Schrodinger, MOE, Discovery Studio, etc.
3. Proficient command of at least one programming language (Python, C, C++, Perl, Shell, …)
4. Highly motivated, possess excellent communication skills, enjoy working in multidisciplinary teams and are fluent in English
5. Experience in AI/machine learning, data mining, and automate workflows is a plus
6. Experience in the pharmaceutical industry or postdoctoral research in the drug discovery context would be a plus
7. Good understanding of drug discovery principles including the fundamentals of medicinal chemistry, ADME/PK and disease biology is a big plus
8. A track record of scientific contributions illustrated by publications and/or patents.
In addition, there are also AIDD scientist positions
有意者请联系：投递请标注：XX岗位+姓名+毕业院校+最高学位 VX：KSX0928
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发表于 Post on 2025-1-22 09:59:57
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